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Ciclofosfamida (Cyclophosphamide)
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Cyclophosphamide

Ciclofosfamida belongs to a class of drugs called alkylating agents. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Ciclofosfamida works by stopping or slowing the growth or spread of certain cancer cells.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Having a set of density functions that work in all scattering regimes provides a framework for modeling wave propagation in random media, facilitating random media characterization, imaging in and through scatter, and random laser design. To investigate the preoperative risk factors of portal venous thrombosis (PVT) after splenectomy and gastric pericardial devascularization in patients with liver cirrhosis and portal hypertension. The peculiarities of tissue sclerosis after injection of autologous bone marrow multipotent mesenchymal stromal cells transfected with GFP gene and stained with Vybrant CM-Dil cell membrane dye were studied by light microscopy with luminescence.

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Post-operative aspirin use and colorectal cancer-specific survival in patients with stage I-III colorectal cancer. Objective tests are more advisable, but to date they are time consuming and expensive.

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We show that it is possible to study effects that occur on different time scales independently without data reduction using the photocatalytic reduction of p-nitrothiophenol as a showcase system. To compare the effectiveness of overlap repair versus end-to-end repair following OASIS in reducing subsequent anal incontinence, perineal pain, dyspareunia and improving quality of life. Randomization was to alirocumab 75/150 mg every 2 weeks or control for 24 to 104 weeks, added to background statin therapy in 8 trials. Increased susceptibility to cortical spreading depression in an animal model of medication-overuse headache. When complexed with a cationic fusogenic peptide, KALA, the ODN/PEG conjugate self-associated to form polyelectrolyte complex micelles in an aqueous solution.

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The sacral-femoral-pubic angle (SFP) has been previously described as a reproducible method to estimate pelvic tilt on a pelvis AP view. Here, this model was used to analyze the gene expression profile associated with the early steps of age-related cell transformation. Characterization of positive-selection-inducing peptides has revealed that the low-affinity TCR engagement by the positive-selection-inducing pMHC complexes initiates intracellular signals that induce the survival of immature thymocytes and their differentiation into mature T cells. Pulsatile venoarterial perfusion using a novel synchronized cardiac assist device augments coronary artery blood flow during ventricular fibrillation.

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A high-resolution human contact network for infectious disease transmission. A transumbilical incision is performed, and a single-incision platform is introduced. Choline precursors promote repair and growth of cell membranes in neurologic diseases, so FCH PET/CT uptake could be explained by repair processes during early outcome of acute ischemic stroke. We propose to measure interlayer conductivity in Josephson-coupled layered superconductors as a function of the strength and the orientation of the parallel magnetic field. Bafetinib, a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.

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Despite the absence of polymeric chitin in vertebrates, chitinases and chitinase-like proteins (CLPs) are well conserved in vertebrate species. Risk assessment in ICU patients using commonly used prognostic models may be influenced using different data definitions and by errors in data collection.

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Simulation of optical properties of polymer substrates coated with a single-particle MSN layer indicates that the surface has a low and graded refractive index in the direction of the thickness and effectively decreases the reflectance of visible light. For patients with advanced cancer treated by PHCTs, the use of classification schemes and decision trees based on specific symptoms can help clinicians predict survival at 7 and 30 days. Since the publication of guidelines for preoperative risk stratification by the American College of Cardiology/American Heart Association in 1996 and the American College of Physicians in 1997, three clinical trials have shown that beta-blocker therapy reduces the risk for perioperative cardiac events.

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To examine the relationships among immunization pain outcomes (pain reactivity, pain regulation and parent ratings of infant pain) over the first year of life and parent report of early temperament. To examine prospectively the association of psychological distress with the development of the metabolic syndrome (MetS) and the potential influence of demographic characteristics, health behaviors, and inflammation in this association. Blockade of microglial KATP -channel abrogates suppression of inflammatory-mediated inhibition of neural precursor cells. The 2010 third national epidemiological survey questionnaire of children with asthma was used for screening for possible patients.

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This study aims to identify potentially modifiable risk factors for MesI mortality through analysis of peri- and intraoperative perfusion data. Only one other case exists regarding the successful use of the splenic vein turndown technique in blunt abdominal trauma. ACE I/D Gene Polymorphism in Children with Family History of Premature Coronary Disease.

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Trends in the care and prevention of developmental disabilities. Protein and mRNA expressions were measured by Western blot and RT-qPCR. A new vector for the high level expression of chimeric antibodies in myeloma cells. Stachybotrys chartarum is a filamentous mold frequently identified among the mycobiota of water-damaged building materials. Patient safety officers thought their organizations should reevaluate the support currently provided by their EAPs, and consider additional peer support mechanisms.

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Through interactions among the three Kai proteins, the phosphorylation states of KaiC generate circadian oscillations in vitro in the presence of ATP. This chapter discusses a systems identification analytic approach to the study of linguistic neural representation. IL-17 enhances tumor development in carcinogen-induced skin cancer. Moreover, only in the HCC group, miR-18a, miR-100, miR-145 and miR-223 were up-regulated 3.48-, 2.95-, 2.12- and 3.91-fold, respectively, and miR-200a and miR-222 were down-regulated 2.56- and 2.00-fold, respectively.

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Matrix metalloproteinases (MMPs) are the main enzymes implicated in ECM degradation. We found that the primary palate in turtles develops similarly to other amniotes, but secondary palate ontogeny diverges. Association of anti-human leukocyte antigen and anti-angiotensin II type 1 receptor antibodies with liver allograft fibrosis after immunosuppression withdrawal. Contact with participants was made through national support organizations and questionnaires were returned by mail. Besides weight loss, patients experience a cluster of symptoms including anorexia, early satiety, and weakness.

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The direct glucuronidation explains why microsomal stability (reflective of phase I metabolism) did not translate to in vivo metabolic stability. The present study clarified that U-Cd was significantly associated with increased mortality, indicating the worsened life prognosis of the general population in Cd non-polluted areas in Japan. Ram spermatozoa cocultured with epithelial cell monolayers: an in vitro model for the study of capacitation and the acrosome reaction. Implementing this long-term monitoring methodology consistently in pulmonary rehabilitation programs could contribute to evaluation of the comparative effectiveness of various treatment options. A chronic hemodialysis patient, previously splenectomized because of trauma in conjunction with gastrectomy, developed bacteremia with type 18 Streptococcus pneumoniae and died within 13 hours of onset of symptoms.

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In HUVEC and in the human microvascular endothelial cell line HMEC-1, hemin treatment as above resulted in protection against cytotoxicity, but not in bovine aortic endothelial cells (BAECs), where such toxicity was potentiated. To investigate the change of the levels of fasting plasma endotoxin (ET) and assess its correlated factors in individuals with different glucose tolerances and body mass indices. Correlation of initial DNA damage detected by alkaline comet assay and clinical endpoints in lung cancer patients Review of CMOS Integrated Circuit Technologies for High-Speed Photo-Detection. Premedication Use Before Nonemergent Intubation in the Newborn Infant.

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A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. We explored the awareness regarding causes, consequences and preventive measures of obesity among 325 ever-married aged 20-54 years women with different levels of body mass index (BMI) in the national capital territory of Delhi representing urban India. Systemic barriers identified suggest the need for enhanced coordination of care across systems such as drug and alcohol treatment, homeless services, and criminal justice and for ready access to outpatient services to reduce crisis psychiatric service use.

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Cerebrospinal fluid leaks and encephaloceles of temporal bone origin: nuances to diagnosis and management. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. Receptor substances of brain mitochondria sensitive to neuromediators

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Cirrhosis-related complications are a major cause of morbidity and mortality in areas where its risk factors are endemic. The aim of the study was to analyse the lifetime of Soletra implantable pulse generators (IPG) in deep brain stimulation (DBS) of the globus pallidus internus (GPi) for dystonia, depending on stimulation parameters and the total electrical energy delivered (TEED) by the IPG. He developed general fatigue, fever, drowsiness and difficulty in walking. A more effective strategy to ensure more appropriate objectives is proposed. BKT140 treatment induced morphological changes, phosphatidylserine externalization, decreased mitochondrial membrane potential, caspase-3 activation, sub-G1 arrest, and DNA double-stranded breaks.

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The acquisition of resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) remains a major challenge in lung cancer medicine. We provide new evidence in support of the routine use of multimodal analgesia that includes scheduled i.v.

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A deconvolution approach is presented here with Tikhonov regularization to correct the photoacoustic/thermoacoustic signals, which resulted in improved reconstructed images by reducing the blurring effect. Clinical estimation of the efficiency of various operative techniques of treatment of ANP at various stages of disease has been made. The greatest challenges to the successful communication of the infant feeding guidelines were related to slowness of communication, inaccessible jargon-ridden English language in the manuals, lack of summaries, lack of supportive supervision to make the guidelines comprehensible, and the absence of a reading culture. Also, cue exposure--whether in vivo or imaginal--may help deal with urges prompted by such cues. The following outcome measures were used in this study: the American Shoulder and Elbow Surgeons (ASES) score, the University of California, Los Angeles (UCLA) Shoulder Rating Scale, the Constant score, and range of motion.

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Reactive oxygen species and reactive nitrogen species (ROS/RNS) play an important role in cell signaling pathways. The octamer-binding transcription factor 4 (Oct4) is essential for maintaining the self-renewal and pluripotency of embryonic stem cells (ESCs).

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CTLA4 A49G polymorphism shows significant association with glioma risk in a Chinese population. Thus, cyanate compromises endothelial functionality in vitro and in vivo.

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However, treatment of mutant cells with thapsigargin (a SERCA antagonist that raises cytosolic calcium levels), resulted in a pronounced decrease in mitochondrial calcium uptake, increased production of reactive oxygen species (ROS), mitochondrial depolarization and fragmentation, and cell viability loss. Compounding this problem is the growing prevalence of methicillin-resistant S. Noonan syndrome and biventricular hypertrophic obstructive cardiomyopathy. Exome sequencing and diffusion tensor imaging in developmental disabilities. Developmental patterns of mucin gene expression in human fetal small intestinal xenografts maintained in severe-combined immunodeficient mice.

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Volume-based metabolic tumor response to neoadjuvant chemotherapy is associated with an increased risk of recurrence in breast cancer. A systematic review was undertaken to examine whether patients with chronic fatigue syndrome (CFS) differ from healthy sedentary controls in physiological exercise capacity, physical activity level and muscle strength. We propose here and explore the hypothesis that plant hormones play roles in animal-microbiota relationships, with consequences for human health. The administration of Y-27632 ultop 20 mg ulotka netto may be a novel strategy for conquering hepatic I/R-induced injury.

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