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Bicalutamide

Bicalutamide is a hormone-based chemotherapy. The NCI Drug Dictionary defines the compound as a “synthetic, nonsteroidal anti-androgen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors.” Bicalutamide is used in combination with other agonists like leuprolide or goserelin for the treatment of metastatic prostate cancer. It works by blocking the normal effect of the male hormone androgen. The main type of androgens produced by the body are testosterone and dihydrotestosterone (DHT). These are formed in testes, adrenal glands and tumors themselves, and they stimulate the growth of prostate cancer cells. Bicalutamide blocks this ability in order to stop the growth and spread of cancer.

Other names for this medication:
Bicalutamide, Casodex, Bicalox, Bicalutamida, Bicusan, Bidrostat, Caluran, Calutide, Calutol, Capro, Cosudex, Imda, Lutamidal, Probic, Zolacos,

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To assess the knowledge on hepatitis B virus (HBV) infection and associated factors among expectant mothers in an endemic region. Hypersensitivity reactions to metals are uncommon, but they are reported and require appropriate evaluation and management, particularly if they are symptomatic. Cytosolic FBPase is relatively conserved among various organisms both at amino acid and nucleotide sequence levels.

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Moreover, poor glycemic control was associated with decision-making function both in behavioral and brain activity in the VMPFC and OFC in patients. For instance, these brainstem pathways may have significant implications not only for the regulation of central hypothalamic and extra-hypothalamic targets but also the autonomic nervous system. The method is exemplified with the application to several plant taxa, and its significance and limits are discussed in the light of current phylogenetic knowledge of these groups. The control group (group 2) consisted of 14 patients in whom only PVE was performed. Relationship between Primary and Secondary Dental Care in Public Health Services in Brazil.

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Prevalence of mental health disorders among children and adolescents living in southern Chile The high potential of MTGase in developing commercial noodles and pasta products is successfully demonstrated. Bacterial infection prevalence study: consecutive patients with cirrhosis were enroled over a six-month period in 13 Italian centres. Effects of GABA-analogues on the high-affinity uptake of GABA in astrocytes in primary cultures. Brain metastasis in renal cancer patients: metastatic pattern, tumour-associated macrophages and chemokine/chemoreceptor expression.

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Fast, Accurate Localization of Epileptic Seizure Onset Zones Based on Detection of High-Frequency Oscillations Using Improved Wavelet Transform and Matching Pursuit Methods. Three patients have been identified in our practice over a period of two years, with different symptoms that influenced the decision of the treatment modality, which were: watch and wait, endoscopic sinus surgery, or endoscopic sinus surgery plus orbitoplasty. We found that the frequency of crossing platforms and the percentage of time spent in the target quadrant were lower in rats exposed to EMF for 28 days than in rats exposed to EMF for 14 days and unexposed rats. Contraction regulates heart development via a complex mechanotransduction process controlled by various mechanical forces. Exploring the association between targeting, child benefits and child poverty across 26 countries.

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Thickened edematous mucosal and submucosal layers at the pyloric antrum have the potential to cause the high frequency of HPS in CNS. We propose an optical pseudoscopic to orthoscopic conversion method for integral imaging using a lens-array holographic optical element (LAHOE), which solves the pseudoscopic problem. We speculate that a hierarchically organized system of face processing areas extends bilaterally from the inferior occipital gyri to the vATLs, with facial representations becoming increasingly complex and abstracted from low-level perceptual features as they move forward along this network. Time-dependent changes of zinc speciation in four soils contaminated with zincite or sphalerite. This study presents evidence that the expression of chemokine receptors in the brain is modulated by two neurotrophins in an area-specific manner.

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In all our hypoxic rats there was evidence of both right and left ventricular hypertrophy. Conditions and methods are chosen which permit isolating melittin and phospholipase in a pure form. Consequently, basing therapeutic decisions on cytology with cut-offs defined for IHC induces a risk that patients will receive suboptimal therapy.

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It is also necessary for trials to be carried out in developing countries and in differing socioeconomic groups in developed countries. This indicates that DOC protects fish from physiological stress associated with UVR exposure and helps maintain production of ECC under conditions of UVR exposure. We suggest that simultaneous OPLL and OLF in this area has a relatively poor recovery and may be very challenging and risky to treat, regardless of the surgical method selected, and recommend early surgery for OPLL and OLF in the mid-thoracic spine.

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The need for additional procedures during a segmental elective colectomy is considered to lead to increased postoperative morbidity, but there have been few data that have validated and quantified this risk. Fatal cases of asthma in the 1-34 year age group should be reported! Effects of jazz on postoperative pain and stress in patients undergoing elective hysterectomy. The levels of resistin and other adipokines in patients with hypothyroidism

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Manipulating visual-motor experience to probe for observation-induced after-effects in adaptation learning. The disorder, a form of Batten disease, is uniformly fatal, with clinical signs starting between 2 and 4 years of age and death usually occurring by the early teenage years. We have considered in the first place a model of the isolated active site coordinated with imidazole and imidazolate to mimic the effects of a very strong H-bond.

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Both spatial and biological information are necessary in order to perform true optimization of a treatment plan and for predicting clinical outcome. Our results suggest that the release of cytochrome c from mitochondria and its subsequent activation of caspase 9 and caspase 3 in testes play a key role in cocaine-induced germ cell apoptosis. Exploring the antigenic features of Fasciola hepatica rediae (Trematoda: Digenea) through the evaluation of different antigenic candidates for further monoclonal antibody generation. This study was carried out to determine the incidence and risk factors o fsystemic reactions caused by SIT treatment, using extracts of different inhalant allergens, adsorbed in aluminium hydroxide and biologically standardized with the major allergens quantified in mass units.

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CR can improve HDL function, and it is beneficial for secondary prevention. With the economic crisis, there has been a further worsening of the conditions of workers. Enzymatic activity of the NS2B-NS3(pro) precursor incorporating a full-length NS2B cofactor of dengue virus type 2 was examined by using synthetic dodecamer peptide substrates encompassing native cleavage sequences of the NS2A/NS2B, NS2B/NS3, NS3/NS4A and NS4B/NS5 polyprotein junctions.

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carbonic anhydrases and l-galactono-1,4-lactone dehydrogenase (GLDH), which catalyzes the last step of ascorbate biosynthesis. Genomics and proteomics have emerged as key technologies in biomedical research, resulting in a surge of interest in training by investigators keen to incorporate these technologies into their research.

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We present an analytical model for spatiotemporal dynamics of ITP-AC. Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR. Convergence of synapses, endosomes, and prions in the biology of neurodegenerative diseases.

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Although cognition has been investigated in individuals with schizophrenia and in non-schizophrenic cocaine abusers, few studies have focused on cocaine-abusing schizophrenics. An investigation into corneal enzymatic resistance following epithelium-off and epithelium-on corneal cross-linking protocols.

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Reconstruction of the corresponding mutants confirmed their specific involvement in induction of SOS by low aminoglycoside concentrations. Unsedated colonoscopy is available worldwide, but is not a routine option in the United States (US).

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She was hospitalized and a ring pessary was inserted after bladder catheterization. A combined calcium--fat staining with determination of vessel wall permeability Since this method is now validated for arms without lymphedema, we plan to validate this new technique for patients with lymphedema.

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The rate of discrepancies likely to affect patient management in this domain is not different from emergent non-ECG-synchronized chest CT. Enhancing performance of uricase using multiwalled carbon nanotube doped polyaniline.

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ricinus was already known to be the most important vector of the tick borne encephalitis virus, and of protozoans of the Babesia genus. Insufficient self-care is an independent risk factor for adverse clinical outcomes in Japanese patients with heart failure. The size of the diaphragmatic defect and a severe cardiac anomaly are strongly associated with outcome.

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This review summarizes the recent genomic discoveries in melanoma in the era of targeted therapy and their implications for functional PET imaging. Unfortunately, a number of patients ultimately developed resistance by multiple mechanisms. Notes from the field: measles transmission at a domestic terminal gate in an international airport - United States, January 2014.

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During experimental tuberculosis (TB), IL-27 prevents optimal antimycobacterial protection and limits the pathological sequelae of chronic inflammation. Our meta- analysis results indicated that upregulated PLCE1 is significantly associated with an increased risk of tumor progression in ESCC and GCA. The ACE-27 assessment was compared with comorbidities captured through hospital discharge face sheets using ICD coding. The deficiency of soluble proteins and plastid ribosomal RNA in the albino pollen plantlets of rice. Thus, Jag1b uses two distinct mechanisms to form three sensory cristae in zebrafish.

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Bone morphogenetic protein-4 expression characterizes inductive boundaries in organs of developing zebrafish. Deep sleep was determined from the HRV signal and verified by delta power from the EEG recordings. The global composition of fatty acids in the PD ACC is altered in a way that increases susceptibility to peroxidation in a region-specific manner. The Effect of Age on Optic Nerve Axon Counts, SDOCT Scan Quality, and Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in Rhesus Monkeys. Hit-or-miss representation of a pattern spectrum and its optical implementation.

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Patient height and weight were measured to calculate body mass index (BMI). Cost analysis of iliac stenting performed in the operating room and the catheterization lab: A case-control study.

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This report describes dental anomalies specific to SIOD that could facilitate diagnosis. Policy, Politics, and the Power of Information: The Critical Need for Outcomes and Clinical Trials Data in Policy-Making in the Schools. Within the cytoplasm, most of the tubular inclusions were stained with the label located on the external granular coat of the nucleocapsid. As such, identifying covert physiological measures that are associated with this off-task state could inform theories of mind-wandering and lead to interventions that improve task focus.

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A promising alternative to graphene oxide, which has been widely used as a platform to prepare the graphene-derived materials but suffers from some intrinsic disadvantages, is thus developed. Partitioning of cotinine across red blood cells and haematocrit effects were investigated. retiruga is known only from the mesomediterranean to supramediterranean belts of the Mediterranean region. Nine of the children had a mutation affecting the gene POU3F4 on Xq21. Maxillofacial fractures predominantly occur in young men, due to interpersonal violence.

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The reprogramming of the peptidoglycan precursor biosynthesis is based on the action of VanHAX or paralogous enzymes as it was shown for Amycolatopsis balhimycina. The variables studied were: age, region from the state, socio-economic situation, previous postectomy, smoking, time from the beginning of injury to diagnosis, staging of the primary lesion, tumor differentiation, treatment performed and death due to cancer. As failure with chlorhexidine was experienced, it was replaced with povidone-iodine for routine handwashing and topical application to patients in affected wards.

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We report the experimental observation and control of space and time-resolved light-matter Rabi oscillations in a microcavity. Coupled axial rotation generally occurred in the same direction with lateral bending. Members of the transforming growth factor beta type (TGFbeta) superfamily and their receptors are expressed in the testis, and are believed to play important paracrine and autocrine roles during testicular development and spermatogenesis. This study examined the relationship between cognitive motivations, demographic characteristics, related preventive health behaviors, and intention to obtain a first screening mammogram among Greek Cypriot women. Evaluation of the concentrations and distribution of carbonyl compounds in selected areas of a Brazilian bus terminal.

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Properties and reactions of pteridines carrying functionalised side chains at the 3-position. The value of the molecular information obtained from saliva is dependent on the use of in vitro and in silico techniques. Traumatic brain injury (TBI) is characterized by an abrupt blow or exchange of force against the head and can be categorized as mild, moderate, and severe. Our results showed that verapamil caused the greatest reduction in the mRNA level while other synthetic (piracetam, phenobarbital) and natural (codeine, cyclosporine A, quercetin) substances showed a selective inhibitory effect. The Deep approach was associated with work environments perceived to be Supportive-Receptive and offer Choice-Independence.

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The German version of the Nurse-WIS appears to be a valid instrument with satisfactory predictive capabilities for recording an impending long-term sick leave. The two methods were compared for their accuracy and sensitivity to detect the stress response using an enzyme assay method as a standard. Both CHIKV strains infected connective tissue fibroblasts of the muscle, but only the LR2006 OPY1 strain replicated within myofibers in vivo, despite similar growth of the two strains in these cell types in vitro. The expression of VEGF and AFP proteins was detected by immunofluorescence.

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Although hantaviruses are not generally considered neurotropic, neurological complications have been reported occasionally in patients with hemorrhagic fever renal syndrome (HFRS). Kinetics and mechanisms of degradation of the antileukemic agent 5-azacytidine in aqueous solutions. However, patient selection for reirradiation remains challenging.

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In the 1970s,Paul Tessier published his craniofacial principles for the primary treatment of craniosynostosis. TcB cutoffs between 6 and 12 mg/dL were evaluated for their negative predictive values (NPVs) for high risk (HR) and for the combination of high-intermediate risk and HR on the Bhutani TSB risk nomogram. The prevalence of major depression, number of attempts and recent life events, methods used, feeling in deliberate self-harm individuals. In this laboratory, we have found that the effect on alignment follows approximately linear rules, with the inducing segment having its greatest influence when its orientation is near to that of the segment being judged.

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Cardiac glycoside poisoning can occur from ingestion of various plants and animal toxins, and the venom gland of cane toad (Bufo marinus) contains large quantities of cardiac glycosides. Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier. The first record in Mexican waters of albinism and synophthalmia (partial cyclopia) in the Pacific angel shark, Squatina californica is presented. In particular, we show how the statistical analysis enabled by our techniques provides new insight into the combustion process. The comparative safety of analgesics in older adults with arthritis.

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The presented model allows the simulation of all implant stages of a central catheter. Ongoing trials would determine in the next several years whether checkpoint inhibitors can have a similar effect in localized disease as they have had in metastatic bladder cancer.

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Neonatal paraesophageal hernia with intrathoracic gastric volvulus is very rare in the newborn period. Secondary outcomes assessed over 24 months were addiction severity, health-related quality of life, utilization of medical and addiction services and HIV risk behaviors. Malignant peripheral nerve sheath tumor (MPNST) is a highly aggressive disease with a dismal prognosis. Their cross-reactivity was further strengthened by studying the capacity of antibodies to tolerate dilution in enzyme immunoassay and reactivity with synthetic TPO/MPO peptides. The results indicate unexpected elements of uniformity shared by the several myosins, such as a three-banded, electrophoretic pattern of light chains in sodium dodecylsulfate (SDS) gels and a low degree of alkaline lability.

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Daily wheel use is thus affected by cage enrichment, but only slightly. Guided tissue regeneration in endodontic surgery by using a bioactive resorbable membrane.

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Two whole-body and static-gamma camera images were taken of patients on days 4 and 7 after the infusion. An experimental investigation of sonic air, CO2 and Helium transverse jets in Mach 5 cross flow was carried out over a flat plate. In vitro and in vivo evaluation of WGA-carbopol modified liposomes as carriers for oral peptide delivery. Prevalence of diabetes is on an increase in India, currently there is limited nation-wide data regarding the prevalence of chronic complications in diabetic patients at diagnosis. A cross-reaction with other members of the genus Moraxella or other moraxella-like organisms was not observed, except with an equine Moraxella sp, which produced a weak reaction.

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Analysis was repeated using 2002-2003 (early) and 2007-2008 (late) 2-year databases. CE exhibited its anti-diabetic effect independently from insulin by at least two mechanisms: i) upregulation of mitochondrial UCP-1, and ii) enhanced translocation of GLUT4 in the muscle and adipose tissues. For patented drugs, external price referencing may encompass the largest impact on drug shortages. Molecular and phenotypic characteristics of maturity-onset diabetes of the young compared with early onset type 2 diabetes in China. Metabolomic Evaluation of Neutrophilic Airway Inflammation in Cystic Fibrosis.

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The presence of Helicobacter pylori infection in children was confirmed by Giemsa staining of gastric biopsy specimens. Decrease in dose requirement of d-tubocurarine by volatile anesthetics. Under an unequal variance signal detection model, pre-experimental knowledge increased both the variance and the separation of the target and foil memory miravirsen dose of colors strength distributions, boosting hits and correct rejections.

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Allelopathic polyacetylenes fromCentaurea repens (Russian knapweed). using a monoclonal antibody that cross-reacted with both C-19 and herperax ointment definition C-21 metabolites. Drinking was not significantly related to measures of perceived social support.

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The influence of birth spacing on child survival in Bangladesh: a life table approach. disruption of subscapularis-supraspinatus tear margin: comparison of clinical outcomes and structural integrity between the two clinda cure capsules for sale techniques. These studies provide extensive support for the proposal that E 600-resistant acid naphthyl butyryl and lauryl esterase activities in human tissues derive largely from the enzyme acid lipase. The aim of this study was to investigate a possible link between a single vaccination against tick-borne encephalitis (TBE) and the appearance of one or more new cerebral lesions in magnetic resonance imaging (MRI) and/or a clinical relapse of MS.

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In very high-risk patients receiving combination haploidentical single-unit cord blood transplants, we have added 4 Gy TBI to the widely used fludarabine, melphalan conditioning regimen, in hopes of reducing relapse and decreasing graft rejection. SpO2 monitoring during skin-to-skin care in the delivery room was well accepted by the midwife. Among the Ino(-) mutants oronazol shampoo for hair involved in stress response, many exhibited phenotypes that are strengthened at elevated temperature and/or when choline is present in the medium. Coefficient of quartile variation was used to measure variability.

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The level of P-gp expression was estimated using phycoerythrin-conjugated anti-P-gp monoclonal antibody 17F9. Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer. Results showed that cases of obesity were more frequent among students who mepral 10 mg indicazioni nazionali were good sleepers.

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Identifying Novel Regulators of Vacuolar Trafficking by Combining Fluorescence Imaging-Based Forward Genetic Screening and In Vitro Pollen Germination. In this paper we present the application of the method to the depramil citalopram for anxiety calibration of the Tilted Wave Interferometer. Understanding the immunobiology of GVHD and developing effective preventions and treatments are critical to the continuing success of AHSCT.

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A gantry rotation is discretized into 180 beam angles and for each beam angle, only one MLC aperture is allowed. Sleep complaints and their association with comorbidity and health-related quality of life in an older population in Sweden. Children in GGC were demographically different from those in other areas of Scotland, being significantly axagon 20 mg prezzo oro more likely to live in the most deprived areas, yet no difference was found in relation to the mental health of preschool-aged children in GGC.

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Models that demonstrate high quality and distribute costs over time should be evaluated to encourage survivors to receive recommended care. Magnetic resonance imaging of the intraluminal thrombus in abdominal aortic aneurysms. The present review highlights the chemopreventive and therapeutic effects, molecular targets and antineoplastic adcirca doses mechanisms that contribute to the observed anticancer activity of chrysin. The dual role of HOP2 in mammalian meiotic homologous recombination.

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This reading frame is initiated at two alternative ATG codons, the second of which is probably the in vivo translation start. From this information, accuracy of species labeling and comparison of constituent to labeled content were assessed. A new database that details the prevalence and management of chronic conditions will make it easier to monitor patients with long-term conditions, the Department jeanne valax during pregnancy of Health (DH) in England has said.

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The aim of the present national prospective population-based study was to assess the early morbidity of esophageal atresia (EA). This review discusses the current evidence for the role of bone marrow adipocytes in tumour growth within the bone marrow microenvironment and the development of the associated bone disease. Fine-needle aspiration study of cystic papillary thyroid carcinoma: Rare cytological findings. After benchmarking our implementation on small benzene derivatives by explicitly reconstructing the Casida eigenvectors from farcet huntingdonshire uk RT-TDDFT, we demonstrate the performance of the method by analyzing the plasmon resonances of icosahedral silver nanoparticles up to Ag561.

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Cardiopulmonary exercise test parameters at rest, omezole 20 hovid vitamin at the anaerobic threshold, at peak exercise and at 1-minute recovery were recorded, including systolic and diastolic blood pressure, the heart rate, O2 consumption, CO2 production, ventilation and the respiratory rate. Chronic kidney disease and underdiagnosis of renal insufficiency among diabetic patients attending a hospital in Southern Ethiopia. Expression of dopamine transporter in the different cerebral regions of methamphetamine-dependent rats. We attempted to critically appraise the available evidence supporting the perceived benefits of rasburicase in the management of TLS.